After writing up my tutorial regarding getting WinBUGS running on a Mac in R, a friend sent me this fantastic simple tutorial on the same thing for OpenBUGS on a mac in R. So, for those that want it, install away! Looks a good bit simpler, actually!
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Or you could use JAGS and rjags which is straightforward to install and doesn’t require the use of Wine at all.
Indeed! Some folk, for various reasons (i.e., collaborations, etc.) do need to do this, though, so, good to have all of the options on the table!